MHP : DREN

Transform Your Body and Alter Your Mind

• Mesolimbic Beta Agonist Fat Burning Agent*
• The Most Powerful Thermogenic Fat Burner*
• Extreme “Feel Good” Sensation*
• Helps Curb Appetite*
• Exclusive Beta-Methoxy Phenylethylamine

Researchers are calling the discovery of an exclusive new element, Beta-Methoxy- Phenylethylamine, a bigger breakthrough than ephedra. Scientists have been studying the basic form Beta-Phenylethyamine (also called Beta-PEA) for years, but unfortunately its short half-life prohibited this element from ever being very effective. The first attempt to overcome the short half-life was to combine Beta-PEA with MAO inhibitors, but this also didn’t work. However, this new form isn’t just showing promise, its showing fantastic results. And while Beta-Methoxy-Phenylethylamine is the new General in the war against fat, a few good soldiers have been added to Dren for total annihilation of stubborn adipose fat!*

Advanced Pharmacological Approach To Fat Annihilation!

Dren uses an advanced pharmacological approach to trigger the process of lipolysis for maximum fat burning. Dren (patent pending compound name Drenbuterol) belongs to a powerful new class of compounds called mesolimbic Beta Agonist Fat Burning Agents. Its mechanism of action is similar to that of the popular old ECA (ephedra, caffeine, and aspirin) stack. Drenbuterol is a proprietary compound scientifically formulated to stimulate both metabolic and mesolimbic pahtways for extreme thermogenic fat burning and neurotropic “feel good” sensory input.*

Each Dren capsule provides the maximum 409mg dose of Drenbuterol and should only be administered once daily and not be used with other stimulants. When taken as directed, Dren will help stimulate the thermogenic fat burning process, increase energy levels, suppress appetite, and elicit a state of heightened mental euphoria.*

Step 1: Sympathometic Thermogenic Activation:

Beta-Methoxy Phenylethylamine (also called Beta-Methoxy PEA) is an exciting new ingredient used exclusively in Dren. Beta-Methox-PEA works in part by increasing noradrenaline (NA) release from sympathetic nerve terminals. As a sympathomimetic, Beta-Methoxy PEA acts to stimulate the sympathetic nervous system. It does this by causing pre-synaptic nerve terminals to release norepinephrine, or what is commonly called noradrenaline (NA), into the synaptic space. It also has the effect of boosting circulating adrenaline, the body’s chief beta-2 agonist. Noradrenaline, once released into the synaptic space, interacts with adrenergic receptors on the surface of adipocytes (fat). This starts a sequence of events within the adipocyte that increases lipolysis (the breaking down of fatty acids) by the enzyme hormone sensitive lipase (HSL). This fat burning effect is dependent on long and steady activation of the receptor by the agonist and is what makes the discovery of Beta-Methoxy PEA so critical and why it is much more effective than other Beta-PEA Formulas.*

Beta-Methoxy PEA is the most effective B-PEA beta-agonist by virtue of its long half-life (stays in the body longer) as well as its ability to be absorbed in fat tissue and better permeate the blood/brain barrier. Comparatively, the half-life of many other Beta-PEA forms is only minutes as the enzyme MAO-B quickly metabolizes them and are less lipophilic which prevents significant concentrations from reaching the brain— therefore no psychoactive and weight loss effect is achieved. As mentioned previously, while the inclusion of MAO-inhibitors would seem to work the evidence shows otherwise. Beta-Methoxy PEA does not have to worry about being broken down by MAO-B due to its unique configuration. The beta “Methoxy” moiety on this compound defends it and allows for increased absorption across the blood brain barrier and deep penetration into the fatty tissues of the brain where it interacts with the aDrenergic receptors. This increase in noradrenaline and adrenergic receptors activation increases cAMP levels in fat cells (increasing its breakdown) and muscle cells (increasing protein synthesis). Beta-Methoxy-PEA’s unique configuration or moiety is what gives it its long duration of action, its extraordinary ability to saturate fat tissue and extremely powerful fat burning effects. I can’t emphasize the point enough: it’s the “Methoxy” in Beta-Methoxy-PEA that makes it simply unrivaled to all other forms of Beta PEA no matter what jargon you read–and its only located in Dren!*

Additionally, Beta-Methoxy Phenethylamine’s enhanced moiety and ability to further penetrate the blood brain barrier elicits extreme euphoric “feel good’ neuro-sensory. Beta-Methoxy-PEA, is an alkaloid and monoamine, therefore, it is thought to function as a neuromodulator or neurotransmitter and inflict extreme psychoactive effects on the body while burning body fat at an unforeseen rate. To sum it up, Beta-Methoxy Phenethylamine freely enters the brain barrier and triggers a cascading release of norepinephrine, dopamine and serotonin and stimulates the mesolimbic reward pathway, resulting in euphoria and sensory excitement.*

Step 2: The Inclusion of an Alpha 2 Agonist works to further Enhance Beta-Methoxy PEA fat burning!

While Beta-Methoxy-PEA by itself is an incredibly effective thermogenic, the scientists at MHP wanted to take fat burning to a new level. Let’s face it — ever since the FDA banned ephedra everyone has been searching for an alternative. MHP didn’t only want to create an ephedra alternative, we were looking to take it way beyond the ECA stack. Once we isolated Beta-Methoxy-PEA and saw its similar yet superior mechanisms of actions as ephedra we knew we could do it.*

In reply to Beta-Methoxy-PEA’s beta-adrenergic stimulation, negative feedback mechanisms are activated as well. This negative feedback garnered can shutdown lipolysis (fat burning). The alpha 2 receptor, phosphodiesterases and adenosine try to slow down or halt the fat burning process. In the case of Dren, Beta-Methoxy-PEA encounters these negative feedback mechanisms. Therefore, measures had to be taken to maximize Beta-Methoxy-PEA’s actions in the body and limit the effects of these negative feedback mechanisms.*

All forms of Beta-PEA are believed to be non-selective adrenergics through the release of noradrenaline because they don’t just active one type of receptor. Regretfully, noradrenaline functions as its own negative feedback signal by activating both the beta and alpha adrenergic receptors. Remember, the stimulation of beta receptors is good as it initiates the fat burning process, but the Alpha 2 receptors actually shut down lipolysis (fat burning). In response, MHP scientists added Yohimbine HCL to the Dren formula to bypass Alpha 2 receptor binding and increase the effectiveness of Dren. Yohimbine HCL is a selective alpha 2 antagonist and can thus short circuit this feedback loop, maximizing noradrenaline levels and the overall fat loss actions of Beta-Methoxy PEA. What we have made is a mechanism of action which is long acting activation on the beta receptor with minimal to no activity at the alpha receptor. This results in the most powerful thermogenic activity in adipose tissue possible.*

Step 3: Phosphodiesterase Inhibitibiton and Adenosine Receptor Interference

Individuals like caffeine because of its stimulatory and energizing effects. However, caffeine has a much more important role than that in Dren. Stimulation of Beta-adrenergic receptor also means a surge in phosphodiesterase and adenosine activity. Phosphodiesterase (PDE) acts to hydrolyze cAMP into inactive fragments while adenosine inhibits cAMP acculumation stopping the stimulation of HSL and the fat burning process. Caffeine harnesses the ability to inhibit phosphodiesterases within the cell and has even been shown to have the ability to inhibit some re-uptake of norepinephrine while also acting as an adenosine receptor blocker. As you can see, caffeine offers important powerful synergies to maximize Dren’s fat burning effects.*

Step 4: Powerful Psycho-active “Feel Good” Neurostimulation

The mind is a powerful thing! Dren will not only transform your body with the most powerful fat burning thermogenic experience, it will also change your mind and put you is a place you want to be: “On Top of The World”. There is no denying it: Beta-Methoxy-PEA is very psycho-active and triggers a euphoric “feel good response”. To further increase Dren neuromodulator activity L-5-Hydroxytryptophan has also been mixed into the formula. L-5-Hydroxytryptophan is a naturally-occurring amino acid, a precursor to the neurotransmitter serotonin which is a monoamine neurotransmitter with feel good and appetite control properties. L-5-Hydroxtryptophan like Beta-Methoxy-PEA also passes through the blood brain barrier into the brain. Its psychoactive action is thought to originate from its effect on serotonin synthesis in central nervous system tissue. It is thought that a high supply of L-5-Hydroxytryptophan I responsible for the brain’s serotonin-producing neurons to increase production leading to increased serotonin release. The serotoninergic system is responsible for helping to modulate mood, emotion, sleep and appetite and thus is occupied in the control of numerous behavioral and physiological functions. L-5-Hydroxytryptophan helps to make sure serotonin and norepinephrine levels remain in balance therefore increasing metabolism and fat loss through synergistic actions with other ingredients in Dren. The end result is an extraordinary “feel good” state of euphoria.*

The fact is, Dren (Drenbuterol) belongs to a powerful new class of elements called mesolimbic beta agonist, which have extremely potent fat burning and euphoric activity and should be taken with caution. Dren stimulates both metabolic and mesolimbic pathways for extreme thermogenic fat burning and neurotropic “feel good” sensory.*

Each Dren capsule has the maximum 409mg dose of Drenbuterol, should only be taken once daily, and should not be used with other stimulants. When taken correctly, Dren will help spur thermogenic fat burning, increase energy levels, decrease appetite and provoke a state of heightened mental euphoria.

Frequently Asked Questions

How does it work?

Dren uses an advanced pharmacological approach to trigger the process of lipolysis for maximum fat burning called Beta-Methoxy Phenylethlyamine (Beta-Metoxy PEA). Dren belongs to a powerful new class of compounds called mesolimbic Beta Agonist Fat Burning Agents. Dren poses more selective and powerful beta-adrenergic fat burning activity than similar products. Dren also has powerful psycho-active euphoric effects.*

Who should take it?

Dren should be consumed by anyone looking for extreme fat burning, steady “no crash” energy and extreme mental focus.

How should I take it?

1 capsule of Dren should be taken 30-45 minutes before workout. On non-workout days, take 1 capsule before breakfast.

Did you know?

Dren is the fat burner to contain the very powerful ingredient Beta-Methoxy Phenylethlyamine (Beta-Metoxy PEA).

Stacking with Dren

Razor Ripped Stack

• Dren
• Xpel
• NO-Bomb
• IsoFast 50

Get Razor Ripped. Dren provides powerful thermogenic and euphoric activities that allow you to burn body fat while putting your body in a good sensory mood. Xpel is a natural diuretic that will shed away water from your belly and inner thighs and give you a toned, firm look. Xpel will also help aid in last minute touch ups. NO-Bomb will help to increase energy endurance, increase fat loss and provide focus during workouts. The IsoFast 50 is a low carb, low calorie whey isolate protein loaded with BCAAs, aminos and glutamine that will aid in your recovery process and burning body fat.*

Showtime Stack

• Dren
• Xpel
• IsoFast 50
• Dark Rage

Showtime Stack. Dren will burn off that unwanted stubborn belly fat and keep you feeling positive throughout the day. Xpel a natural diuretic will help you shed unwanted water weight and leave your body looking in showtime shape. The IsoFast 50 is a low carb, low calorie pure whey isolate protein shake that will enhance your performance as well as increase your recovery rate and maximize your lean muscle gains. Dark Rage carb free will intensify your workout and give you an extra edge in getting showtime ready!*

Fat Loss Stack

• Dren
• IsoFast 50
• NO-Bomb
• Xpel

Fat Loss Stack. Dren will melt pounds with only one pill a day, keeping your body in a state of thermogenesis as well as in a state of euphoria with a feel good attitude all day. IsoFast 50 low calorie, low carb whey protein isolate will surely pack on the muscle while keeping the fat off. No-Bomb powerful nitric oxide will give you increased energy and focus through your workouts. Xpel is a natural diuretic that will surely touch up your body and bring out striations and curves that you might have never even knew existed.*